847698-97-9

Upstream product

• 350013-78-4 [2-(3,4-Dimethoxy-benzoylamino)-ethyl]-carbamic acid tert-butyl ester 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 1370335-15-1 C₁₉H₂₂N₂O₅ 
• 93-07-2 Veratric acid 

Downstream Products

• 203860-27-9 4,4'-bis(1-carbonyl-2-(4'-carbonyl-1',2'-dimethoxyphenyl)-1,2-bis(aminoethyl)benzene)-2,2'-bipyridine 
• 1261242-31-2 N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-3,4-dimethoxybenzamide 

Relevant academic research and scientific papers

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF and RAF1 kinases. Compound 1zb is the most potent agains

Broad-spectrum antiproliferative activity of a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives

This article described the synthesis and in vitro antiproliferative activities a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives. The nine target compounds were tested for in vitro antitumor effect against a

Synthesis of new 6-(4-Fluorophenyl)-5-(2-substituted pyrimidin-4-yl) imidazo[2,1-b] thiazole derivatives and their antiproliferative activity against melanoma cell line

Synthesis of a new series of pyrimidinyl-imidazo[2,1-b]thiazole derivatives is described. Their antiproliferative activity against A375 human melanoma cell line was tested and the effect of substituents on the pyrimidinyl ring side chain was investigated.

Potassium cation induced switch in anion selectivity exhibited by heteroditopic ruthenium(II) and rhenium(I) bipyridyl bis(benzo-15-crown-5) ion pair receptors

Cl- and H2PO4- anion selectivity properties of new heteroditopic RuII and ReI bipyridyl bis(benzo-15-crown-5) receptors are remarkably dependent upon the presence of co-bound intramolecular sandwich crown ether complexed K+.

Cooperative binding of potassium cation and chloride anion by novel rhenium(I) bipyridyl amide crown ether receptors

New rhenium(I) bipyridyl amide crown ether receptors are prepared and shown to complex K+Cl- ion pairs in which crown ether complexation of the potassium cation cooperates in the binding of chloride anion.