847740-67-4Relevant academic research and scientific papers
Construction of Stable Metal–Organic Framework Platforms Embedding N-Heterocyclic Carbene Metal Complexes for Selective Catalysis
Kim, Hyunyong,Kim, Hyunseok,Kim, Kimoon,Lee, Eunsung
supporting information, p. 18687 - 18697 (2021/12/17)
We report a bottom-up approach to immobilize catalysts into MOFs, including copper halides and gold chloride in a predictable manner. Interestingly, the structures of MOFs bearing NHC metal complexes maintained a similar 4-fold interpenetrated cube. They
N-SULFONYL AMIDINE SYNTHESIS VIA THREE-COMPONENT COUPLING REACTION USING HETEROGENEOUS COPPER CATALYST
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Paragraph 0088-0094; 0096-0102; 0129; 0130; 0170; 0171, (2018/07/31)
The present invention relates to a method of synthesizing N-sulfonyl amidine. More specifically, the present invention relates to the method of synthesizing N-sulfonyl amidine through a three-component coupling reaction using a heterogeneous copper catalyst; and optimization of reaction conditions applied thereto. The method is able to obtain corresponding N-sulfonyl amidine at high yield with respect to various substrates by performing a three-component coupling reaction of terminal alkyne, sulfonyl azide and amine by using a heterogeneous copper catalyst (Cu@C) obtained by pyrolyzing HKUST-1 which is a type of a metal-organic framework, and enables the heterogeneous copper catalyst to be reused at least four or more times without significant loss of catalytic activities since the heterogeneous copper catalyst has structural stability.COPYRIGHT KIPO 2018
A modular approach for multicomponent synthesis of amidines using modified Scolecite
Jagadale, Megha,Bhange, Pallavi,Salunkhe, Rajashri,Bhange, Deu,Rajmane, Mohan,Rashinkar, Gajanan
, p. 95 - 105 (2015/12/18)
Copper exchanged Scolecite was successfully synthesized and used as an efficient, mild and recyclable catalyst for promoting multi-component synthesis of amidines from 4-toluenesulfonyl azide, phenyl acetylene and variety of substituted amines in THF at ambient temperature in good yields within short reaction time.
N-Sulfonyl amidine synthesis via three-component coupling reaction using heterogeneous copper catalyst derived from metal-organic frameworks
Kim, Myeong Jin,Kim, Bo Ram,Lee, Chang Yeon,Kim, Jinho
, p. 4070 - 4073 (2016/08/18)
Three-component coupling reaction of terminal alkyne, sulfonyl azide, and amine for the synthesis of N-sulfonyl amidine was developed using heterogeneous Cu@C catalyst, which was generated by pyrolysis of HKUST-1 (Cu3(BTC)2, BTC?=?1,
N- Allyl- N- sulfonyl ynamides as synthetic precursors to amidines and vinylogous amidines. An unexpected N-to-C 1,3-sulfonyl shift in nitrile synthesis
Dekorver, Kyle A.,Johnson, Whitney L.,Zhang, Yu,Hsung, Richard P.,Dai, Huifang,Deng, Jun,Lohse, Andrew G.,Zhang, Yan-Shi
supporting information; experimental part, p. 5092 - 5103 (2011/08/06)
A detailed study of amidine synthesis from N-allyl-N-sulfonyl ynamides is described here. Mechanistically, this is a fascinating reaction consisting of diverging pathways that could lead to deallylation or allyl transfer depending upon the oxidation state of palladium catalysts, the nucleophilicity of amines, and the nature of the ligands. It essentially constitutes a Pd(0)-catalyzed aza-Claisen rearrangement of N-allyl ynamides, which can also be accomplished thermally. An observation of N-to-C 1,3-sulfonyl shift was made when examining these aza-Claisen rearrangements thermally. This represents a useful approach to nitrile synthesis. While attempts to render this 1,3-sulfonyl shift stereoselective failed, we uncovered another set of tandem sigmatropic rearrangements, leading to vinyl imidate formation. Collectively, this work showcases the rich array of chemistry one can discover using these ynamides.
