847776-62-9Relevant articles and documents
Synthesis and acetylcholinesterase inhibition of derivatives of huperzine B
Feng, Song,Xia, Yu,Han, Dongmei,Zheng, Chunyan,He, Xuchang,Tang, Xican,Bai, Donglu
, p. 523 - 526 (2007/10/03)
By targeting dual active sites of AChE, a number of new derivatives of HupB have been synthesized and tested as acetylcholinesterase inhibitors. The most potent compound, bis-HupB 5b is 72-fold more potent in AChE inhibition and 79-fold more selective for AChE versus BChE than HupB.