84782-87-6Relevant academic research and scientific papers
A Novel α-Acrylate Anion Equivalent: A Useful Synthon for α-Substituted Acrylic Esters
Baraldi, Pier Giovanni,Barco, Achille,Benetti, Simonetta,Moroder, Fabio,Pollini, Gian Piero,et al.
, p. 1265 - 1266 (1982)
An efficient preparation of α-substituted acrylic esters is described, based on the Dieckmann-Michael retrograde reactions of the C-alkylation products of 4-methoxycarbonylthiolan-3-one (1).
Methyl 4-Oxothiolane-3-carboxylate and Methyl 2-Methyl-4-oxothiolane-3-carboxylate Anions as Synthetic Equivalents of α-Acrylate and α-Crotonate Anions. Formal Synthesis of Integerrinecic Acid
Baraldi, Pier Giovanni,Guarneri, Mario,Pollini, Gian Piero,Simoni, Daniele,Barco, Achille,Benetti, Simonetta
, p. 2501 - 2505 (2007/10/02)
The base-promoted fragmentation of the C-alkylation products (6a-h) and (8a-e) of methyl 4-oxothiolane-3-carboxylate (4) and methyl 2-methyl-4-oxothiolane-3-carboxylate (5) gave good yields of the α-substituted acrylates (7a-h) and α-substituted crotonate
