84787-51-9

Upstream product

• 116261-03-1 (R)-4-Amino-tetrahydro-pyran-2-one 
• 501-53-1 benzyl chloroformate 
• 138878-11-2 (R)-tert-Butyl 3-Amino-5-(tert-Butyldimethylsiloxy)pentanoate 
• 77856-52-1 (S)-3-<(benzyloxycarbonyl)amino>-4-(methoxycarbonyl)butyric acid 
• 116173-89-8 [(R)-3-(tert-Butyl-dimethyl-silanyloxy)-1-((S)-4-isopropyl-4,5-dihydro-oxazol-2-ylmethyl)-propyl]-carbamic acid tert-butyl ester 
• 138878-04-3 (R)-5-(tert-Butyl-dimethyl-silanyloxy)-3-(3,5-dihydro-4-aza-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-pentanoic acid tert-butyl ester 
• 138877-98-2 (E)-tert-butyl 5-(tert-butyldimethylsilyloxy)pent-2-enoate 

Downstream Products

• 84823-06-3 (5R,6R)-3-((S)-(E)-2-Acetylamino-ethenesulfinyl)-6-(1-hydroxy-1-methyl-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 79244-00-1 (5R,6R)-3-((R)-(E)-2-Acetylamino-ethenesulfinyl)-6-(1-hydroxy-1-methyl-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 84823-05-2 (5R,6R)-3-((E)-2-Acetylamino-vinylsulfanyl)-6-(1-hydroxy-1-methyl-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 92620-31-0 2-Diazo-4-[(2R,3R)-3-(1-hydroxy-1-methyl-ethyl)-4-oxo-azetidin-2-yl]-3-oxo-butyric acid 4-nitro-benzyl ester 
• 84787-57-5 (5R,6R)-6-(1-Hydroxy-1-methyl-ethyl)-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 
• 76025-73-5 carpetimycin A 
• 92530-27-3 2-Diazo-4-[(2R,3R)-3-(1-methyl-1-trimethylsilanyloxy-ethyl)-4-oxo-azetidin-2-yl]-3-oxo-butyric acid 4-nitro-benzyl ester 
• 84787-59-7 4-[(2R,3R)-3-(1-Methyl-1-trimethylsilanyloxy-ethyl)-4-oxo-azetidin-2-yl]-3-oxo-butyric acid 4-nitro-benzyl ester 
• 84787-53-1 methyl syn-3-<(benzyloxycarbonyl)amino>-5-hydroxy-2-<(1-hydroxy-1-methyl)ethyl>pentanoate 

Relevant academic research and scientific papers

An Asymmetric Ammonia Synthon for Michael Additions

The highly diastereoselective 1,4-addition of lithiated chiral amine 1 to α,β-unsaturated esters, followed by hydrogenolysis of the benzylic-type C-N bonds of the 1,4-adducts, provides an asymmetric ammonia synthon for Michael additions.Under optimized co

NEW SYNTHESIS OF β-AMINO ACIDS BY NUCLEOPHILIC ADDITION OF ENOLATE ANIONS TO N-METHOXYCARBONYLIMINES GENERATED FROM α-METHOXY CARBAMATES.

The nucleophilic addition of enolate anions of alkyl acetates to N-methoxycarbonylimines generated from α-methoxy carbamates gave β-amino acid derivates (3) and enantioselective synthesis (72-90percentee) of 3 was achieved by using chiral 2-methyloxazolines instead of acetates.