847872-05-3

Basic information

• Product Name: Phenol, 2,5-difluoro-4-(phenylazo)-
• CAS NO: 847872-05-3
• Molecular Formula: C12H8F2N2O
• Molecular Weight: 234.205
• Mol File: 847872-05-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phenol, 2,5-difluoro-4-(phenylazo)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,5-difluoro-4-(phenylazo)-(847872-05-3)
• EPA Substance Registry System: Phenol, 2,5-difluoro-4-(phenylazo)-(847872-05-3)

Safety Data

• Hazardous Substances Data: 847872-05-3(Hazardous Substances Data)

Upstream product

• 2713-31-7 2,5-difluorophenol 
• 62-53-3 aniline 

Downstream Products

• 120103-19-7 4-amino-2,5-difluorophenol 
• 849702-94-9 5-fluoro-4-heptyloxy-2-(propylthio)azobenzene 
• 849702-85-8 2,5-difluoro-4-(heptyloxy)azobenzene 

Relevant articles and documents

Activation of chlorine and fluorine by a phenylazo group towards nucleophilic aromatic substitution. Regioselective preparation of polysubstituted anilines

A phenylazo group was used for selective activation of ortho fluorine and chlorine atoms towards nucleophilic aromatic substitution with the propanethiolate anion. This enabled a regioselective synthesis of three substituted 4-alkoxyanilines. The regioselectivity of substitution was confirmed by comparison of experimental NMR chemical shifts with empirically predicted values. The observed reactivity of the substrates is discussed in the context of the substituent effect.