84794-09-2Relevant academic research and scientific papers
Pd-catalyzed decarboxylative cross-coupling of 2-carboxyazine N-oxides with various (hetero)aryl halides
Rouchet, Jean-Baptiste,Schneider, Cedric,Spitz, Cedric,Lefevre, Johan,Dupas, George,Fruit, Corinne,Hoarau, Christophe
supporting information, p. 3610 - 3615 (2014/04/03)
Decarboxylative cross-coupling reactions of substituted 2-carboxyazine N-oxides, with a variety of (hetero)aryl halides, by bimetallic Pd 0/CuI and Pd0/AgI catalysis are reported. Two possible pathways, a conven
Ascorbic acid as an initiator for the direct C-H arylation of (hetero)arenes with anilines nitrosated in situ
Crisostomo, Fernando Pinacho,Martin, Tomas,Carrillo, Romen
supporting information, p. 2181 - 2185 (2014/03/21)
Ascorbic acid (vitaminC) has been used as a radical initiator in a metal-free direct C-H arylation of (hetero)arenes. Starting from an aniline, the corresponding arenediazonium ion is generated in situ and immediately reduced by vitaminC to an aryl radical that undergoes a homolytic aromatic substitution with a (hetero)arene. Notably, neither heating nor irradiation is required. This procedure is mild, operationally simple, and constitutes a greener approach to arylation. Copyright
Antiallergic agents. 2. N-(1H-tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides
Honma,Oda,Hashiyama,Hanamoto,Nakai,Inoue,Ishida,Takeda,Ono,Tsuzurahara
, p. 1499 - 1504 (2007/10/02)
A new series of N-(1H-tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides was prepared to determine the effects of substituents on the benzene and pyridine rings on antiallergic activity in the rat passive cutaneous anaphylaxis (PCA) assay after oral administr
