848072-61-7

Basic information

• Product Name: Oxiranemethanamine, N-[3-(4-methoxyphenoxy)-3-phenylpropyl]-N-methyl-
• CAS NO: 848072-61-7
• Molecular Formula: C20H25NO3
• Molecular Weight: 327.423
• Mol File: 848072-61-7.mol

Chemical Properties

• CAS DataBase Reference: Oxiranemethanamine, N-[3-(4-methoxyphenoxy)-3-phenylpropyl]-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranemethanamine, N-[3-(4-methoxyphenoxy)-3-phenylpropyl]-N-methyl-(848072-61-7)
• EPA Substance Registry System: Oxiranemethanamine, N-[3-(4-methoxyphenoxy)-3-phenylpropyl]-N-methyl-(848072-61-7)

Safety Data

• Hazardous Substances Data: 848072-61-7(Hazardous Substances Data)

Upstream product

• 56161-79-6 N-methyl-3-phenyl-3-(4-methoxyphenoxy)propanamine 
• 106-89-8 epichlorohydrin 

Relevant articles and documents

Substituted propanolamines and alkylamines derived from fluoxetine as potent appetite suppressants

A series of propanolamine and alkylamine analogues of fluoxetine (7-26, 28-31) were synthesized and assessed for their anorexigenic and antidepressant activities. Effect of various substituents at C-4 aryl position of fluoxetine has also been studied. Most of the propanolamine analogues (7-13, 16-26) displayed significant anorexigenic activity but interestingly they were devoid of antidepressant activity whereas anorexigenic as well as antidepressant activity was retained in the alkylamine series (28-31). Compounds 10 and 26 emerged as the most active compound and anorexigenic activity was better (83.67% and 82.45%) compared to fluoxetine (81.25%).