848072-80-0

Basic information

• Product Name: Ethanone, 1-[3-[(phenylsulfonyl)methyl]phenyl]-
• CAS NO: 848072-80-0
• Molecular Formula: C15H14O3S
• Molecular Weight: 274.34
• Mol File: 848072-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[3-[(phenylsulfonyl)methyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[3-[(phenylsulfonyl)methyl]phenyl]-(848072-80-0)
• EPA Substance Registry System: Ethanone, 1-[3-[(phenylsulfonyl)methyl]phenyl]-(848072-80-0)

Safety Data

• Hazardous Substances Data: 848072-80-0(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 823-78-9 meta-bromobenzyl bromide 
• 111-34-2 -butyl vinyl ether 
• 130891-01-9 1-bromo-3-((phenylsulfonyl)methyl)benzene 

Downstream Products

• 848072-81-1 [1-(3-benzenesulfonylmethyl-phenyl)-2-bromo-ethoxy]-tert-butyl-dimethyl-silane 

Relevant articles and documents

Tryptamine-based human β3-adrenergic receptor agonists. Part 3: Improved oral bioavailability via modification of the sulfonamide moiety

The continued SAR investigation of tryptamine-based human β3-adrenergic receptor (AR) agonists is reported. Prior efforts resulted in the identification of 2 as a potent β3-AR agonist. Further modification of the left side arylsulfonamide portion in 2 provided compounds with good cell permeability, which have potent agonistic activity for β3-AR. Cinnamylamine analog 16i exhibited an excellent agonistic profile in vitro and good oral bioavailability in rats.