848085-28-9

Upstream product

• 1118916-80-5 4,5-dimethyl-1,3-bis-(2,4,6-trimethylphenyl)-3H-imidazol-1-ium chloride 
• 88-05-1 2,4,6-trimethylaniline 
• 75105-48-5 N,N'-dimesitylformamidine 

Relevant academic research and scientific papers

Organic Redox Systems Based on Pyridinium-Carbene Hybrids

New redox systems with three oxidation states are highly sought-after, for example, for redox-flow battery applications, selective reducing agents, or organic electronics. Herein, we describe a straightforward and modular synthesis of a new class of such

Method for efficiently synthesizing 4, 5-dimethyl-1, 3-disubstituted aryl carbene

The invention discloses a method for efficiently synthesizing 4, 5-dimethyl-1, 3-disubstituted aryl carbene. The method includes the steps: dissolving 4, 5-dimethyl-N, N-2(2, 4, 6-trimethylphenyl) imidazolethione in dry reaction solvents under protection of high-purity nitrogen or argon, adding metal potassium, and performing heating reflow reaction for 4-8h; filtering mixture after reaction, washing filter residues, combining washing liquor and filter liquor, performing pressure reacting concentration on the filter liquor, washing obtained solids by the aid of organic washing solvents to obtain colorless 4, 5-dimethyl-N, N-2(2, 4, 6-trimethylphenyl) imidazole-2-carbene. According to the method, used raw materials are low in cost and easy to acquire, and the method is low in production cost, high in yield, mild in reaction condition, simple and safe to operate and less in environmental pollution and has high popularization and application values.

Rhodium-catalyzed borylation of aryl 2-pyridyl ethers through cleavage of the carbon-oxygen bond: Borylative removal of the directing group

The rhodium-catalyzed reaction of aryl 2-pyridyl ethers with a diboron reagent results in the formation of arylboronic acid derivatives via activation of the C(aryl)-O bonds. The straightforward synthesis of 1,2-disubstituted arenes was enabled through catalytic ortho C-H bond functionalization directed by the 2-pyridyloxy group followed by substitution of this group with a boryl group. Several control experiments revealed that the presence of a sp2 nitrogen atom at the 2-position of the substrate and the use of a boron-based reagent were crucial for the activation of the relatively inert C(aryl)-O bond of aryl 2-pyridyl ethers.

Backbone tuning in indenylidene-ruthenium complexes bearing an unsaturated N-heterocyclic carbene

The steric and electronic influence of backbone substitution in IMes-based (IMes = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2- ylidene) N-heterocyclic carbenes (NHC) was probed by synthesizing the [RhCl(CO)2(NHC)] series of complexes to quantify