848128-91-6 Usage
Description
4-Hydroxy-8-cyanoquinoline is a versatile chemical compound characterized by the presence of a hydroxyl and a nitrile group on a quinoline ring. This unique structure endows it with distinctive reactivity and biological properties, making it a promising candidate for pharmaceutical and agrochemical development. The hydroxyl group facilitates interactions with biological targets, while the nitrile group serves as a versatile functional group for further chemical modifications, contributing to its potential in drug discovery and development.
Uses
Used in Pharmaceutical Development:
4-Hydroxy-8-cyanoquinoline is utilized as a building block in the synthesis of various heterocyclic compounds, which are prevalent in drug development. Its unique structure allows for the creation of new pharmaceutical agents with potential therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, 4-Hydroxy-8-cyanoquinoline serves as a key intermediate in the synthesis of bioactive molecules, contributing to the development of novel agrochemicals with improved efficacy and selectivity.
Used in Chemical Synthesis:
4-Hydroxy-8-cyanoquinoline is employed as a versatile intermediate in organic synthesis, enabling the production of a wide range of chemical compounds with diverse applications across various industries. Its reactivity and functional groups make it a valuable component in the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 848128-91-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,1,2 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 848128-91:
(8*8)+(7*4)+(6*8)+(5*1)+(4*2)+(3*8)+(2*9)+(1*1)=196
196 % 10 = 6
So 848128-91-6 is a valid CAS Registry Number.
848128-91-6Relevant articles and documents
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities
Madrid, Peter B.,Sherrill, John,Liou, Ally P.,Weisman, Jennifer L.,DeRisi, Joseph L.,Guy, R. Kiplin
, p. 1015 - 1018 (2007/10/03)
A simple two-step synthesis method was used to make 51 B-ring-substituted 4-hydroxyquinolines allowing analysis of the effect of ring substitutions on inhibition of growth of chloroquine sensitive and resistant strains of Plasmodium falciparum, the dominant cause of malaria morbidity. Substituted quinoline rings other than the 7-chloroquinoline ring found in chloroquine were found to have significant activity against the drug-resistant strain of P. falciparum W2.
