848129-47-5Relevant academic research and scientific papers
Ceric ammonium nitrate-mediated detritylation of tritylated amines
Pattanayak, Sankha,Sinha, Surajit
supporting information; experimental part, p. 34 - 37 (2011/02/25)
Efficient deprotection of tritylated amines to the corresponding amines mediated by 20 mol % ceric ammonium nitrate [Ce(NH4) 2(NO3)6, CAN], 10 equiv of acetic acid and 15 equiv of water in dichloromethane is presented. This method equally worked well in the case of morpholino nucleosides.
A convenient method for the preparation of primary amines using tritylamine
Theodorou, Vassiliki,Ragoussis, Valentine,Strongilos, Alexandros,Zelepos, Evangelos,Eleftheriou, Argyro,Dimitriou, Maria
, p. 1357 - 1360 (2007/10/03)
A simple method for the preparation of primary amines by treating N-tritylamines with trifluoroacetic acid has been established. The N-tritylamines were prepared by the reaction of alkyl halides or alkyl p-toluenesulfonates with tritylamine, or by the reaction of alkyl bromides with lithium tritylamide.
