848133-35-7

Basic information

• Product Name: trans-4-Dimethylaminocrotonic acid hydrochloride
• Synonyms: (e)-4-(dimethylamino)-2-butenoic acid hydrochloride;trans-4-Dimethylaminocrotonic acid hydrochloride;TRANS-4-DIMETHYLAMINOCROTONIC ACID HCL;2-BUTENOIC ACID, 4-(DIMETHYLAMINO)-, HYDROCHLORIDE;(E)-4-(dimethylamino)but-2-enoic acid hydrochloride;4-DiMethylaMino-But-2-Enoic Acid Hcl Salt;Afatinib intermediate E;(2E)-4-(diMethylaMino)but-2-enoic acid hydrochloride
• CAS NO: 848133-35-7
• Molecular Formula: C6H12ClNO2
• Molecular Weight: 165.62
• EINECS: 1592732-453-0
• Product Categories: Others chemical reagents;Amines;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 848133-35-7.mol

Chemical Properties

• Melting Point: 162 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: trans-4-Dimethylaminocrotonic acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Dimethylaminocrotonic acid hydrochloride(848133-35-7)
• EPA Substance Registry System: trans-4-Dimethylaminocrotonic acid hydrochloride(848133-35-7)

Safety Data

• Hazardous Substances Data: 848133-35-7(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

trans 4-Dimethylaminocrotonic acid HCl is a reagent used in the preparation of tyrosine kinase inhibiting antitumor agents.

InChI:InChI=1/C6H11NO2.ClH/c1-7(2)5-3-4-6(8)9;/h3-4H,5H2,1-2H3,(H,8,9);1H/b4-3+;

Upstream product

• 848133-10-8 (2E)-4-(1H-IMIDAZOL-4-YL)BUT-2-ENOIC ACID 
• 848133-09-5 (2E)-4-PYRROLIDIN-1-YLBUT-2-ENOIC ACID 
• 848131-14-6 MONOISOHEXYLPHTHALATE 
• 848130-90-5 3-Hydroxy-5-methylphenyl benzoate 
• 848130-11-0 N-ethyl-N-isopropyl-tryptamine 
• 848128-91-6 4-HYDROXY-8-CYANOQUINOLINE 
• 848128-87-0 4-Hydroxy -6-isopropylquinoline 
• 848128-81-4 4-HYDROXY-5-METHYLQUINOLINE 
• 84812-84-0 benzhydryl 2-(benzothiazol-2-yldithio)-alpha-[1-[(methylsulphonyl)oxy]ethylidene]-4-oxo-3-[(phenoxyacetyl)amino]azetidine-1-acetate 
• 848127-98-0 Ir(dpq)2(acac) 
• 848127-77-5 Methyl 6-chloro-1-Methyl-1H-indole-5-carboxylate 
• 84812-73-7 4-(3-oxobutyl)phenyl 2-methylbutyrate 
• 84812-72-6 4-(3-oxobutyl)phenyl 2-methylcrotonate 
• 84812-71-5 4-(3-oxobutyl)phenyl isovalerate 

Downstream Products

• 848133-74-4 2-PROPENOIC ACID, 3-[[4-(ACETYLAMINO)-3-ETHOXYPHENYL]AMINO]-2-CYANO-, ETHYL ESTER 
• 848133-75-5 Acetamide, N-(3-cyano-7-ethoxy-4-hydroxy-6-quinolinyl)- 
• 848133-76-6 n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide 
• 848133-87-9 6-AMINO-4-CHLORO-7-ETHOXYQUINOLINE-3-CARBONITRILE 
• 848133-88-0 (E)-N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(diMethylaMino)but-2-enaMide 
• 848134-27-0 Benzenamine, 3-chloro-4-(1-naphthalenylmethoxy)- 
• 848135-96-6 7-Bromo-3-methyl-1,2,3,4-tetrahydro-isoquinoline hydrochloride 
• 848138-16-9 2-Cyclododecen-1-ol,2-fluoro-,(2Z)-(9CI) 
• 848138-82-9 5-(VINYLSULFAMIDO)-TETRAZOLE 
• 848138-85-2 3-(VINYLSULFAMIDO)-1,2,4-TRIAZOLE 
• 848138-87-4 3-(VINYLSULFAMIDO)-PYRAZOLE 
• 84813-97-8 O-(4-formylphenyl) O-methyl phenylphosphonothioate 
• 848139-78-6 6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile 
• 84814-09-5 1,3-di-tert-butyl-2,2-dimethyl-2,3-dihydro-1H-1,3,2-diazasilole