848142-50-7 Usage
Uses
Used in Pharmaceutical Research:
CMMB is utilized as a research chemical for studying the effects and mechanisms of action of cannabinoid receptors CB1 and CB2. Its potent agonist activity allows researchers to investigate the therapeutic potential of targeting these receptors in various conditions.
Used in Recreational Drug Market:
CMMB is used as a recreational drug due to its psychoactive properties, which can produce euphoric and hallucinogenic effects. However, its high potential for abuse and addiction, as well as the lack of understanding of its long-term health effects, make it a dangerous and potentially harmful substance.
Used in Drug Abuse and Addiction Studies:
The high potential for abuse and addiction associated with CMMB makes it a subject of interest for studies on drug abuse and addiction. Research on CMMB can help in understanding the factors contributing to substance abuse and developing strategies for prevention and treatment.
Note: The use of CMMB as a recreational drug is not recommended due to its potential dangers and lack of regulation. The information provided is for educational purposes only and should not be interpreted as an endorsement or promotion of its use.
Check Digit Verification of cas no
The CAS Registry Mumber 848142-50-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,1,4 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 848142-50:
(8*8)+(7*4)+(6*8)+(5*1)+(4*4)+(3*2)+(2*5)+(1*0)=177
177 % 10 = 7
So 848142-50-7 is a valid CAS Registry Number.
848142-50-7Relevant academic research and scientific papers
Indazole estrogens: Highly selective ligands for the estrogen receptor β
De Angelis, Meri,Stossi, Fabio,Carlson, Kathryn A.,Katzenellenbogen, Benita S.,Katzenellenbogen, John A.
, p. 1132 - 1144 (2007/10/03)
The estrogen receptors, ERα and ERβ, are important pharmaceutical targets. To develop ERβ-selective ligands, we synthesized a series of nonsteroidal compounds having a phenyl-2H-indazole core with different groups at C-3. Several of these show high affinity and good ERβ selectivity, especially those with polar and/or polarizable substituents at this site (halogen, CF3, nitrile); the best compounds have affinities for ERβ comparable to estradiol, with ERβ affinity selectivity >100. This potency and ERβ selectivity is also seen in cell-based transcriptional assays, where several compounds showed ERβ efficacies equivalent to that of estradiol with ERβ potency selectivities of 100. These compounds might prove useful as selective pharmacological probes to study the biological actions of estrogens mediated through ERβ, and they might lead to the development of useful pharmaceuticals. These findings also contribute to an evolving pharmacophore that characterizes certain nonsteroidal ligands having high ERβ subtype affinity and potency selectivity.
