848186-86-7Relevant academic research and scientific papers
Structure-activity studies on 1,3-dioxane-2-carboxylic acid derivatives, a novel class of subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists
Asaki, Tetsuo,Aoki, Tomiyoshi,Hamamoto, Taisuke,Sugiyama, Yukiteru,Ohmachi, Shinji,Kuwabara, Kenji,Murakami, Kohji,Todo, Makoto
, p. 981 - 994 (2008/09/17)
A series of 1,3-dioxane carboxylic acid derivatives was synthesized and evaluated for human PPAR transactivation activity. Structure-activity relationships on the phenyloxazole moiety of the lead compound 3 revealed that the introduction of small hydropho
