848243-87-8

Upstream product

• 848243-85-6 ethyl 4H-thieno[3,2-b]pyrrole-2-carboxylate 
• 108-94-1 cyclohexanone 
• 848243-86-7 6-cyclohex-1-en-1-yl-4H-thieno[3,2-b]pyrrole-2-carboxylic acid 

Downstream Products

• 848244-00-8 tert-butyl 5-bromo-6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate 
• 914497-89-5 tert-butyl 6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate 
• 886973-22-4 methyl 6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate 

Relevant academic research and scientific papers

Improved modular synthesis of thieno[3,2-b]pyrroles and thieno[2,3-b]pyrroles

A convenient modular synthesis for the construction of densely functionalized thieno[3,2-b]pyrroles, allosteric inhibitors of the Hepatitis C virus NS5B polymerase, is described. The route allows the introduction of substituents in positions 4, 5, and 6 o

Thienopyrrole compound and use thereof as HCV polymerase inhibitor

The present invention relates to a thienopyrrole compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound as an active ingredient. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.

THIENOPYRROLES AS ANTIVIRAL AGENTS

The present invention relates to thienopyrrole compounds of formula (I); wherein A, B, Y, Ar, n, Z and X1 are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.