848358-81-6

Basic information

• Product Name: 2-amino-4-bromo-5-methylphenol
• Synonyms: 2-amino-4-bromo-5-methylphenol;Phenol,2-aMino-4-broMo-5-Methyl-
• CAS NO: 848358-81-6
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202.05
• Mol File: 848358-81-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 288.3 °C at 760 mmHg
• Flash Point: 128.1 °C
• Appearance: /
• Density: 1.647 g/cm³
• Vapor Pressure: 0.00136mmHg at 25°C
• Refractive Index: 1.653
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.31±0.23(Predicted)
• CAS DataBase Reference: 2-amino-4-bromo-5-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-bromo-5-methylphenol(848358-81-6)
• EPA Substance Registry System: 2-amino-4-bromo-5-methylphenol(848358-81-6)

Safety Data

• Hazardous Substances Data: 848358-81-6(Hazardous Substances Data)

Usage

General Description

2-Amino-4-bromo-5-methylphenol is a chemical compound with the molecular formula C7H8BrNO. It is a derivative of phenol and is commonly used in the manufacturing of hair dyes and coloring agents. 2-amino-4-bromo-5-methylphenol is known for its strong coloration properties and is often used as a direct dye for textiles and inks. 2-Amino-4-bromo-5-methylphenol is classified as a hazardous substance and should be handled with care to avoid skin and eye irritation. It is important to follow safety guidelines when working with this chemical to prevent any potential health risks.

InChI:InChI=1/C7H8BrNO/c1-4-2-7(10)6(9)3-5(4)8/h2-3,10H,9H2,1H3

Upstream product

• 182500-28-3 4-bromo-5-methyl-2-nitrophenol 

Downstream Products

• 857616-88-7 acetic acid-(5-bromo-2-hydroxy-4-methyl-anilide) 

Relevant articles and documents

SUBSTITUTED HETEROCYCLIC COMPOUNDS AS CRAC MODULATORS

The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators. wherein, ring D is Formula (a) or Formula (b): A and B, which may be same or different, are independently CR3 or N; Y is CR3 or N; L is selected from —NR2C(O)—, —C(O)NR2— and —NR2CRaRb—; Ra and Rb are independently hydrogen, halogen or substituted or unsubstituted alkyl; ring E is selected from the Formula (i) to (vii).