848413-78-5

Upstream product

• 479090-19-2 3-(methoxy-methyl-carbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 917-54-4 methyllithium 
• 147369-09-3 7,7-Dichloro-6-oxo-2-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 

Downstream Products

• 848413-79-6 C₂₂H₂₇NO₄ 
• 848413-81-0 3-(1-hydroxy-ethyl)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Microbial Baeyer-Villiger oxidation applied to the synthesis of the N-protected (1R,5R)-Geisman-Waiss lactone

Using whole cell Baeyer-Villiger biooxidation as a key step and depending on the choice of the biocatalyst {E. coli TOP10[pQR239] or Acinetobacter TD63}, the synthesis of nearly enantiopure N-protected (1R,5R)-(-)-Geisman-Waiss lactone (92% ee) or its (1R

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.