848417-25-4

Upstream product

• 141781-18-2 <1-(β-D-ribofuranosyl)thymine>-3'-spiro-5''-<4''-amino-1'',2''-oxathiole 2'',2''-dioxide> 
• 1054632-64-2 [(5S,6R,8R,9R)-9-Hydroxy-6-hydroxymethyl-8-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2λ⁶-thia-spiro[4.4]non-3-en-4-ylamino]-acetic acid methyl ester 
• 848417-21-0 [1-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl]-3-N-(methyl)thymine]-3'-spiro-5''-(4''-methoxycarbonylmethylamino-1'',2''-oxathiole-2'',2''-dioxide) 
• 100-51-6 benzyl alcohol 
• 1053258-63-1 [9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-8-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2λ⁶-thia-spiro[4.4]non-3-en-4-ylamino]-acetic acid methyl ester 

Relevant academic research and scientific papers

Novel [2′,5′-Bis-O-(tert-butyldimethylsily)-β-D- ribofuranosyl]-3′-spiro-5″-(4″-amino-1″, 2″-oxathiole-2″,2″-diozide) derivatives with anti-HIV-1 and anti-human-cytomegalovirus activity

New [2′,5′-bis-O-(tert-butyldimethylsilyl)-β-D- ribofuranosyl]-3′-spiro-5″-(4″-amino-1″, 2″-oxathiole-2″,2″-dioxide) (TSAO) derivatives substituted at the 4″-amino group of the spiro moiety with different carbonyl functionalities have been designed and sy