848440-16-4

Upstream product

• 179688-52-9 6-hydroxy-7-methoxyquinazolin-4(3H)-one 
• 13794-72-4 3H-6,7-dimethoxyquinazolin-4-one 
• 230955-75-6 6-acetoxy-4-chloro-7-methoxyquinazoline 
• 740081-22-5 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl acetate 
• 848440-15-3 4-(3-chloro-2-fluoroanilino)-6,7-dihydroxyquinazoline 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS

The invention concerns quinazoline derivatives of the Formula (I); wherein each of R1, R2, W, X1, X2, Z, a and b are as defined in the description; processes for their preparation; pharmaceutical compositions co

Selective alkylation of a 6,7-dihydroxyquinazoline

A convenient 3-step multi-parallel process for the preparation of 4-(3-chloro-2-fluoroanilino)-6,7-bisalkoxyquinazolines is highlighted.