848469-85-2Relevant articles and documents
Chiral bidentate aminophosphine ligands: Synthesis, coordination chemistry and asymmetric catalysis
Zijp, Eric J.,Van Der Vlugt, Jarl Ivar,Tooke, Duncan M.,Spek, Anthony L.,Vogt, Dieter
, p. 512 - 517 (2005)
Chiral aminophosphines Ph2PN(R)(CH2) nN(R)PPh21-4 [n = 2, R = CH(CH3)(Ph) 1; n = 3, R = CH(CH2CH3)(Ph) 2, n = 2, R = CH(CH3)(1- naphthyl) 3; n = 2, R = CH(CH3)(C6H11) 4] were synthesized by the reaction of ClPPh2 with the appropriate easily accessible enantiopure amine building blocks. For compounds 1 and 2, the corresponding selenides 5 and 6 were prepared to determine the electronic character of the phosphine moieties. By reaction of 1 with either PdCl 2(cod) or PdCl(CH3)(cod) the cis-complexes 7 and 8 were obtained. The molecular structure for complex 7, cis-[PdCl2(1)], was determined by X-ray crystallography. Reaction of PtCl2(cod) with 1 or 2 yielded the corresponding monomeric cis-isomers 9 and 10. The rhodium derivative [RhCl(CO)(1)] (11) was obtained as a mixture of cis and trans-isomers. Preliminary results in the rhodium catalyzed hydroformylation of styrene and vinyl acetate, with ee's up to 51% and high regioselectivities, showed the potential of these chiral aminophosphines for homogeneous catalysis.
