84849-16-1 Usage
General Description
The chemical "(3beta,6beta)-3,5,6,10,16-pentahydroxygrayanotoxan-14-yl 2,2-dimethylpropanoate" is a complex organic compound derived from the grayanotoxin family. It is composed of a grayanotoxin core structure with five hydroxyl groups and a 2,2-dimethylpropanoate ester group. Grayanotoxins are known for their neurotoxic effects, particularly their ability to activate sodium channels and cause symptoms such as dizziness, weakness, and, in severe cases, seizures and cardiac irregularities. The addition of the ester group to the grayanotoxin core may impact its pharmacological properties and potentially alter its toxicity. Overall, this chemical represents a potent and potentially dangerous natural compound with neurotoxic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 84849-16-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,8,4 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 84849-16:
(7*8)+(6*4)+(5*8)+(4*4)+(3*9)+(2*1)+(1*6)=171
171 % 10 = 1
So 84849-16-1 is a valid CAS Registry Number.
84849-16-1Relevant articles and documents
Quantitative Structure-Inotropy Relationship Applied to Substituted Grayanotoxins
Shirai, Naohiro,Sakakibara, Jinsaku,Kaiya, Toyo,Kobayashi, Sawako,Hotta, Yoshihiro,Takeya, Kazumi
, p. 851 - 855 (2007/10/02)
Nine 14β-O-acylated grayanotoxins were synthesized by ozonolysis of 14,16-alkylidenegrayanotoxin III.The correlation between positive inotropic potency (PIE) in guinea pigs and physicochemical parameters (Vw, Mw, and Rm50) in 14,14-substituted
