84853-82-7Relevant academic research and scientific papers
A 'Biogenetic Like' Synthesis of Perloline, 6-(3,4-dimethoxyphenyl)-5-hydroxy-5,6-dihydrobenzonaphthyridin-4(3H)-one
Duong, Thach,Prager, Rolf H.,Were, Stephen T.
, p. 1431 - 1440 (2007/10/02)
9H-Indenopyridine-1(2H),9-dione, prepared by a new efficient route, reacts with 3,4-dimethoxyphenyllithium to form the keto alcohol (7), which rearranges with hydrazoic acid to form 5-(3,4-dimethoxyphenyl)benznaphthyridin-4(3H)-one.The N-oxide photolyses smoothly to yield dehydroperloline as the sole product.
