848566-33-6

Basic information

• Product Name: (3R,4R,5S)-5-(2'-benzyloxy-(1'R)-1'-hydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2(3H)-one
• Synonyms: (3R,4R,5S)-5-(2'-benzyloxy-(1'R)-1'-hydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2(3H)-one
• CAS NO: 848566-33-6
• Molecular Weight: 268.266
• Mol File: 848566-33-6.mol

Chemical Properties

• CAS DataBase Reference: (3R,4R,5S)-5-(2'-benzyloxy-(1'R)-1'-hydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5S)-5-(2'-benzyloxy-(1'R)-1'-hydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2(3H)-one(848566-33-6)
• EPA Substance Registry System: (3R,4R,5S)-5-(2'-benzyloxy-(1'R)-1'-hydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2(3H)-one(848566-33-6)

Safety Data

• Hazardous Substances Data: 848566-33-6(Hazardous Substances Data)

Upstream product

• 144895-69-2 (3E,4E)-ethyl 6-(benzyloxy)hexa-2,4-dienoate 
• 848566-32-5 (E,4R,5R)-ethyl 6-(benzyloxy)-4,5-dihydroxyhex-2-enoate 

Relevant articles and documents

De novo enantioselective syntheses of galacto-sugars and deoxy sugars via the iterative dihydroxylation of dienoate

(Chemical Equation Presented) An efficient route to various sugar lactones has been developed. Key to the overall transformation is the sequential osmium-catalyzed dihydroxylation of 2,4-dienoates. The simplest (one-step/racemic) example of this reaction occurs when the dihydroxylation is performed with aqueous NMO in MeOH. When the first dihydroxylation is performed using the AD-mix procedure, an enantioselective variant results. When a matched AD-mix procedure is used for the second dihydroxylation, an exceedingly diastereo- and enantioselective synthesis of galacto-1,4-lactone results.