848587-25-7Relevant articles and documents
RETRACTED ARTICLE: One-pot synthesis of Hantzsch dihydropyridines using a highly efficient and stable PdRuNi@GO catalyst
Demirci, Tuna,?elik, Betül,Yildiz, Yunus,Eri?, Sinan,Arslan, Mustafa,Sen, Fatih,Kilbas, Benan
, p. 76948 - 76956 (2016)
Addressed herein, highly monodispersed PdRuNi nanoparticles furnished with graphene oxide (PdRuNi@GO NPs) were prepared as novel, stable, efficient and exceptionally reusable heterogeneous catalysts for 1,4-dihydropyridine synthesis via multicomponent con
One-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using a deep eutectic solvent: a green method and mechanistic insight
Nguyen, Vu Thanh,Nguyen, Hai Truong,Tran, Phuong Hoang
supporting information, p. 2053 - 2059 (2021/02/06)
The multicomponent synthesis of 1-amidoalkyl naphthols and polyhydroquinolines has been developed as an atom-economic procedure catalyzed by a deep eutectic solvent ([CholineCl][ZnCl2]3). The reactions proceed smoothly at low temperatures for a short reaction time without the use of toxic and volatile organic solvents. Deep eutectic solvents are capable of not only allowing multicomponent reactions to proceed in high yield but also controlling the selectivity towards desired products. The mechanistic insight was examined by HRMS (ESI) to propose a plausible mechanism. Furthermore, [CholineCl][ZnCl2]3can be recycled in up to three consecutive cycles with an insignificant loss of catalytic activity under the optimized conditions.
Efficient one-pot synthetic methods for the preparation of 3,4-dihydropyrimidinones and 1,4-dihydropyridine derivatives using BNPs?SiO2(CH2)3NHSO3H as a ligand and metal free acidic heterogeneous nano-catalyst
Bahrami, Kiumars,Khodamorady, Minoo,Sohrabnezhad, Samira
, (2020/01/23)
Heterocyclic compounds with biological and pharmacological activates like 3,4-dihydropyrimidin-2-(1H)-ones and 1,4-dihydropyridines have attracted great interest. Boehmite nanoparticles functionalized with silylpropyl sulfamic acid (BNPs?SiO2(C
Synthesis of polyhydroquinolines and propargylamines through one-pot multicomponent reactions using an acidic ionic liquid immobilized onto magnetic Fe3O4as an efficient heterogeneous catalyst under solvent-free sonication
Nguyen, Hai Truong,Tran, Phuong Hoang,Truong, Vy Anh
, p. 25358 - 25363 (2020/07/30)
A nano-sized Fe3O4-supported Lewis acid ionic liquid catalyst for the synthesis of polyhydroquinolines and propargylamines under ultrasound irradiation has been developed. LAIL&at;MNP was synthesized from imidazolium chlorozincate(ii) ionic liquid grafted onto the surface of Fe3O4 nanoparticles and evaluated by FT-IR, TGA, SEM, Raman, TEM, ICP-OES, and EDS. The multicomponent synthesis of polyhydroquinolines and propargylamines proceeded smoothly to afford the desired products in high yields. LAIL&at;MNP can be separated easily from the reaction mixture and reused for several runs without a significant degradation in catalytic activity.
Magnetic Fe3O4 nanoparticles: Efficient and recoverable nanocatalyst for the synthesis of polyhydroquinolines and Hantzsch 1,4-dihydropyridines under solvent-free conditions
Nasr-Esfahani, Masoud,Hoseini, S. Jafar,Montazerozohori, Morteza,Mehrabi, Rasool,Nasrabadi, Hasan
, p. 99 - 105 (2014/01/06)
A green approach for efficient and rapid synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine and polyhydroquinoline derivatives using magnetic Fe3O4 nanoparticles (Fe3O 4 MNPs) as a recyclable catalyst under solvent-free conditions was reported. The catalyst was characterized by FT-IR, XRD, and TEM analysis. Compared to the classical reactions, this method consistently has the advantages of short reaction times, little catalyst loading, high yields, easy magnetic separation and reusability of the catalyst.
Biological activities of eco-friendly synthesized hantzsch adducts
Pacheco, Samira R.,Braga, Taniris C.,Da Silva, Daniel L.,Horta, Livia P.,Reis, Fabiano S.,Ruiz, Ana Lucia T.G.,De Carvalho, Joao E.,Modolo, Luzia V.,De Fatima, Angelo
, p. 889 - 896 (2013/09/23)
Fourteen Hantzsch adducts with different substituents at the C-4 position were synthesized through multicomponent reactions by using citric or lactic acid as catalysts. To the best of our knowledge, this is the first report on the synthesis of such a clas
5-Pyrrolidin-2-yltetrazole-promoted one-pot hantzsch polyhydroquinoline synthesis using NH4HCO3 as nitrogen source
Su, Weike,Li, Jia,Li, Jianjun
experimental part, p. 860 - 863 (2009/04/04)
A straightforward and green synthesis of polyhydroquinoline derivatives was reported via a four-component coupling reaction of aldehydes, dimedone, active methylene compounds, and ammonium bicarbonate in the presence of 5-pyrrolidin-2-yltetrazole under solvent-free conditions. The method offers several advantages including high yields, an environmental friendly procedure, a short reaction time, and easy isolation of products.
