848609-41-6Relevant academic research and scientific papers
Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series
Amblard, Franck,Aucagne, Vincent,Guenot, Pierre,Schinazi, Raymond F.,Agrofoglio, Luigi A.
, p. 1239 - 1248 (2007/10/03)
The synthesis of novel acyclic nucleosides in the 5-alkynyl and 6-alkylfuro[2,3-d]pyrimidine series is described. These compounds were evaluated against HIV and HSV in order to determine their spectrum of antiviral activity. Their cytotoxicities against P
Highly efficient AgNO3-catalyzed preparation of substituted furano-pyrimidine nucleosides
Aucagne, Vincent,Amblard, Franck,Agrofoglio, Luigi A.
, p. 2406 - 2408 (2007/10/03)
An efficient method for the synthesis of substituted furanopyrimidine nucleosides is described. Upon treatment with catalytic AgNO3, 5-alkynyl uracil derivatives were almost quantitatively converted into their corresponding bicyclic nucleoside
