848642-13-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-4-deoxy-α-D-galactopyranose is used as a starting material for the synthesis of various pharmaceutical compounds due to its unique chemical structure and properties.
Used in Chemical Research:
4-Chloro-4-deoxy-α-D-galactopyranose is used as a research compound in the field of organic chemistry to study its properties, reactions, and potential applications in the development of new chemical compounds and materials.
Used in Analytical Chemistry:
4-Chloro-4-deoxy-α-D-galactopyranose can be used as a reference compound in analytical chemistry for the development and validation of analytical methods, such as chromatography and mass spectrometry, for the detection and quantification of impurities in α-D-Galactose and other related compounds.
Used in Biochemical Research:
4-Chloro-4-deoxy-α-D-galactopyranose can be used in biochemical research to study its interactions with enzymes, proteins, and other biomolecules, which may provide insights into its potential biological activities and applications in the development of new drugs and therapies.

Upstream product

• 813413-37-5 1,4:3,6-dianhydro-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside 

Downstream Products

• 955943-44-9 1-(2'-O-tosyl-4'-chloro-4'-deoxy-β-D-galactopyranosyl)propan-2-one-3',6'-ketal 

Relevant academic research and scientific papers

Preparation of α and β anomers of 1,2,3,6-tetra-O-acetyl-4- chloro-4-deoxy-D-galactopyranose based upon anomerization and kinetic acetylation

4-Chloro-4-deoxy-α-d-galactopyranose, 1,2,3,6-tetra-O-acetyl-4- chloro-4-deoxy-α-d-galactopyranose and 1,2,3,6-tetra-O-acetyl-4-chloro-4- deoxy-β-d-galactopyranose were readily prepared from 1,4:3,6-dianhydro- β-d-fructofuranosyl 4-chloro-4-deoxy-α-d-galactopyranoside. In the study, we found an interesting anomerization phenomenon of 4-chloro-4-deoxy-d- galactose. The molar ratio of α and β anomers in solution is about 1:2 when the anomerization reaches a dynamic equilibrium, and the β anomer could completely convert to the α anomer in the process of crystallization and precipitation. The acetylation of 4-chloro-4-deoxy-d-galactopyranose is kinetically controlled, and the configuration of the starting galactose determines the configuration of the resulting acetates. The influence of the chloro group at C-4 and the O-acetyl group at the anomeric carbon on the galactopyranose ring conformations is discussed, based upon the crystallographic data for the α and β anomers of 1,2,3,6-tetra-O-acetyl-4-chloro-4- deoxy-d-galactopyranose.

4'-Halo-substituted sucrose derivatives

Compounds of the general formula (I) STR1 (wherein X represents a halogen atom; R1 and R2 respectively represent a combination selected from the group consisting of: a hydroxy group and a hydrogen atom; a halogen atom and a hydrogen atom; and a hydrogen atom and a halogen atom; and R3 and R4, which may be the same or different, each represent a substituent selected from the group consisting of a halogen atom and a hydroxy group; at least one of R1, R2 and R3 representing a halogen atom) are potent sweeteners obtainable by opening a corresponding 3',4'-lyxoepoxide with a source of halide ions.