848645-69-2Relevant academic research and scientific papers
Metal-free aza-Claisen type ring expansion of vinyl aziridines: An expeditious synthesis of seven membered N-heterocycles
Singh, Deepak,Ha, Hyun-Joon
, p. 3093 - 3097 (2019)
A metal-free approach for the synthesis of 7-membered aza-heterocycles has been developed by the intermolecular [5 + 2] cycloaddition of non-activated vinylaziridines and alkynes. This method has a broad substrate scope under mild reaction conditions to a
DYKAT of vinyl aziridines: Total synthesis of (+)-pseudodistomin D
Trost, Barry M.,Fandrick, Daniel R.
, p. 823 - 826 (2007/10/03)
(Chemical Equation Presented) A concise total synthesis of (+)-pseudodistomin D was developed. The absolute stereochemistry was established through a dynamic kinetic asymmetric cycloaddition of an isocyanate to a vinyl aziridine. The piperidine core was c
