848648-55-5Relevant academic research and scientific papers
Novel procedure for the coupling of sterically hindered electron-deficient anilines to the 6-position of the purine core
Leenders, Ruben,Heeres, Jan,Vandenput, Dirk,Guillemont, Jerome,Lewi, Paul
scheme or table, p. 3246 - 3250 (2011/10/01)
Sterically hindered electron-deficient anilines are coupled to the 6-position of the purine core only when activated as their corresponding TFA-amide. The free anilines did not react under all conditions tested. After aqueous work-up, the TFA-group is los
HIV REPLICATION INHIBITING PURINE DERIVATIVES
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Page/Page column 61, (2010/02/11)
The present invention relates to the use of a compound of formula (I) for the manufacture of a medicament for the prevention or the treatment of HIV infection wherein the compound of formula (I) is a compound of formula (I) a N-oxide, a pharmaceutically a
