848649-38-7

Basic information

• Product Name: 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE
• Synonyms: 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE;2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULPHONATE
• CAS NO: 848649-38-7
• Molecular Formula: C₁₂H₄BrF₅O₃S
• Molecular Weight: 403.12
• Mol File: 848649-38-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 66-68
• Appearance: /
• CAS DataBase Reference: 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE(848649-38-7)
• EPA Substance Registry System: 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE(848649-38-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 848649-38-7(Hazardous Substances Data)

Usage

General Description

2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE is a chemical compound that is a derivative of benzene. It consists of a pentafluorophenyl group attached to a 4-bromobenzenesulfonate group. 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE is often used in organic synthesis and chemical research as a reagent or intermediate. It is known for its high reactivity and is often used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. 2,3,4,5,6-PENTAFLUOROPHENYL 4-BROMOBENZENESULFONATE is also used in the development of new materials and as a building block for the synthesis of more complex organic compounds.

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 5467-74-3 4-Bromophenylboronic acid 

Downstream Products

• 498-83-9 4-bromobenzenesulfonyl fluoride 
• 886021-96-1 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-bromobenzenesulfonate ester 
• 928656-94-4 pentafluorophenyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonate 
• 1375455-82-5 5-methyl-N-(1-methyl-1H-pyrazol-4-yl)-4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-amine 
• 1375457-32-1 perfluorophenyl 4-(5-methyl-2-(1-methyl-1H-pyrazol-4-ylamino)pyrimidin-4-yl)benzenesulfonate 

Relevant articles and documents

Pentafluorophenyl sulfonate ester as a protecting group for the preparation of biaryl- and heterobiaryl sulfonate esters

(Chemical Equation Presented) The use of the pentafluorophenyl (PFP) group as a sulfonic acid protecting group has allowed the synthesis of new biaryl- and heterobiaryl-PFP-sulfonate esters by use of the Suzuki-Miyaura reaction. The successful employment

Copper-Catalyzed Synthesis of Activated Sulfonate Esters from Boronic Acids, DABSO, and Pentafluorophenol

The synthesis of pentafluorophenyl (PFP) sulfonate esters based on the Pd-catalyzed sulfination of aryl and heteroaryl boronic acids is reported. The sulfinate intermediates are converted in situ to the corresponding sulfonate esters using a copper-catalyzed oxidative process, providing a broad range of PFP esters in good yields.

O-HYDROXY- AND O-AMINO BENZAMIDE DERIVATIVES AS IKK2 INHIBITORS

A compound of Formula (I).