848671-27-2

Upstream product

• 190908-91-9 (1-(S)-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-carbamic acid tert-butyl ester 
• 56583-58-5 N-tert-butoxycarbonyl-3-(2-naphthyl)-L-alanine 
• 735258-37-4 3-[((S)-2-Amino-4-methyl-pentanoyl)-((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amino]-propionic acid methyl ester 
• 408540-44-3 3-((S)-1-Methylcarbamoyl-2-naphthalen-2-yl-ethylamino)-propionic acid methyl ester 
• 408540-45-4 3-[((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoyl)-((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amino]-propionic acid methyl ester 

Relevant academic research and scientific papers

1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1

1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1 inhibitors. The synthesis, structure, and biological evaluation of these 1,4-diazepine-2,5-diones and related derivatives are described.