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Usage

Uses

Used in Organic Synthesis:
1-(4-bromophenyl)-2,2,2-trifluoroethyl trifluoromethanesulfonate is used as a reagent in organic synthesis for its ability to transfer its alkyl group to other molecules, leading to the formation of new carbon-carbon bonds. This property makes it a valuable tool in the creation of various organic compounds.
Used in Chemical Reactions:
In the chemical industry, 1-(4-bromophenyl)-2,2,2-trifluoroethyl trifluoromethanesulfonate is used as a reagent in various chemical reactions due to its high reactivity. Its alkylating agent properties allow it to participate in a wide range of reactions, making it a versatile compound for use in the synthesis of different chemical products.

Upstream product

• 421-83-0 trifluoromethane sulfonyl chloride 
• 80418-12-8 1-(4-bromo-phenyl)-2,2,2-trifluoro-ethanol 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 

Relevant academic research and scientific papers

ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Provided are compounds of Formula I as JAK inhibitors, which are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

N-(2-CYANO HETEROCYCLYL)PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.

ACYCLIC CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Solvolysis of 1-Aryl-2,2,2-trifluoroethyl Sulfonates. Kinetic and Stereochemical Effects in the Generation of Highly Electron-Deficient Carbocations

Solvolysis rates of sulfonates XC6H4CH(O3SR)CF3 (R = p-Tol or CF3) correlate with ?+(X) with values of ρ+ between -6.7 and -11.9 depending upon solvent.For the tosylates the rates depend on the solvent parameter YOTs with