848774-90-3 Usage
Uses
Used in Pharmaceutical Industry:
2-Pyridinemethanol,3,6-dimethylis used as a key intermediate in the synthesis of pharmaceuticals for its ability to form stable derivatives with biologically active compounds. It contributes to the development of new drugs with improved therapeutic properties and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Pyridinemethanol,3,6-dimethylis utilized as a building block in the production of pesticides and herbicides. Its unique chemical structure allows for the creation of effective and targeted agrochemicals that can protect crops from pests and diseases while minimizing environmental impact.
Used in Perfumery and Flavoring Industry:
2-Pyridinemethanol,3,6-dimethylis used as a raw material in the manufacturing of perfumes and flavoring agents. Its distinct aromatic properties make it suitable for creating unique and long-lasting scents and flavors in various consumer products.
Used in Chemical Synthesis:
As an intermediate, 2-Pyridinemethanol,3,6-dimethylis employed in the synthesis of other organic compounds. Its reactivity and compatibility with various chemical groups make it a valuable component in the production of specialty chemicals, dyes, and other industrial products.
Safety Precautions:
Due to its potential health hazards if inhaled or ingested, 2-Pyridinemethanol,3,6-dimethylshould be handled with caution. It is essential to work in a well-ventilated area and use appropriate personal protective equipment, such as gloves, goggles, and masks, to minimize exposure risks.
Check Digit Verification of cas no
The CAS Registry Mumber 848774-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,7,7 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 848774-90:
(8*8)+(7*4)+(6*8)+(5*7)+(4*7)+(3*4)+(2*9)+(1*0)=233
233 % 10 = 3
So 848774-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-6-3-4-7(2)9-8(6)5-10/h3-4,10H,5H2,1-2H3
848774-90-3Relevant academic research and scientific papers
Discovery of functionally selective 7,8,9,10-tetrahydro-7,10-ethano-1,2,4- triazolo[3,4-a]phthalazines as GABAA receptor agonists at the α3 subunit
Russell, Michael G. N.,Carling, Robert W.,Atack, John R.,Bromidge, Frances A.,Cook, Susan M.,Hunt, Peter,Isted, Catherine,Lucas, Matt,McKernan, Ruth M.,Mitchinson, Andrew,Moore, Kevin W.,Narquizian, Robert,Macaulay, Alison J.,Thomas, David,Thompson, Sally-Anne,Wafford, Keith A.,Castro, José L.
, p. 1367 - 1383 (2007/10/03)
We have previously identified the 7,8,9,10-tetrahydro-7,10-ethano-1,2,4- triazolo[3,4-a]phthalazine (1) as a potent partial agonist for the 0.3 receptor subtype with 5-fold selectivity in binding affinity over α1. This paper describes a detailed investigation of the substituents on this core structure at both the 3- and 6-positions. Despite evaluating a wide range of groups, the maximum selectivity that could be achieved in terms of affinity for the α3 subtype over the α1 subtype was 12-fold (for 57). Although most analogues showed no selectivity in terms of efficacy, some did show partial agonism at α1 and antagonism at α3 (e.g., 25 and 75). However, two analogues tested (93 and 96), both with triazole substituents in the 6-position, showed significantly higher efficacy for the α3 subtype over the α1 subtype. This was the first indication that selectivity in efficacy in the required direction could be achieved in this series.
