84878-61-5

Basic information

• Product Name: Maduramycin ammonium
• Synonyms: Maduramincin ammonium;Maduramicin ammonium premix;MADURAMICIN AMMONIUM 90%;2H-Pyran-2-acetic acid, 6-(1R)-1-(2S,5R,7S,8R,9S)-2-(2S,2R,3S,5R,5R)-3-(2,6-dideoxy-3,4-di-O-methyl-.beta.-L-arabino-hexopyranosyl)oxyoctahydro-2-methyl-5-(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl2,2-bifuran-5-yl-9-hydroxy-2,8-dimet;Maduraminic Ammonium;Cygro;Maduramicin;Prinicin ammonium
• CAS NO: 84878-61-5
• Molecular Formula: C47H83NO17
• Molecular Weight: 934.16
• EINECS: 200-771-5
• Product Categories: Active Pharmaceutical Ingredients;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API's
• Mol File: 84878-61-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 173-176 °C
• Boiling Point: 938.7 °C at 760 mmHg
• Flash Point: 521.5 °C
• Appearance: White crystalline powder
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: 0-6°C
• CAS DataBase Reference: Maduramycin ammonium(CAS DataBase Reference)
• NIST Chemistry Reference: Maduramycin ammonium(84878-61-5)
• EPA Substance Registry System: Maduramycin ammonium(84878-61-5)

Safety Data

• Hazard Codes: T+
• Statements: 25-27-36
• Safety Statements: 26-28-36/37-45
• RIDADR: UN 2811
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 84878-61-5(Hazardous Substances Data)

Usage

Description

Maduramycin ammonium salt is a white crystalline powder with a melting point of 165-167°C. It is insoluble in water and soluble in organic solvents. Because of its broad anticoccidial spectrum and not easy to develop drug resistance, it is widely used. The dosage is very small. At present, our country stipulates that the amount of maduramycin ammonium salt added to the feed for preventing chicken coccidiosis is 5mg/kg.

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 84878-61-5 differently. You can refer to the following data:
1. Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.
2. Maduramicin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.
3. Polyether antibiotic chemically related to the lonomycins. Coccidiostat

InChI:InChI=1/C47H81NO16.H2O/c1-23-18-24(2)45(9,51)61-36(23)31-19-32(58-35-20-30(53-10)40(55-12)28(6)57-35)42(59-31)44(8)15-14-33(60-44)43(7)16-17-46(64-43)21-29(49)25(3)37(62-46)26(4)38-41(56-13)39(54-11)27(5)47(52,63-38)22-34(48)50;/h23-33,35-42,49,51-52H,14-22H2,1-13H3,(H2,48,50);1H2/t23-,24+,25+,26+,27-,28-,29-,30-,31+,32-,33+,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46+,47+;/m0./s1