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84880-03-5

Cefpimizole is a third-generation cephalosporin antibiotic, characterized by a somewhat narrower spectrum of activity compared to cefotaxime and cefoperazone. It is a semi-synthetic β-lactam antibiotic that is effective against a range of bacteria, including both Gram-negative and Gram-positive organisms.
Used in Pharmaceutical Industry:
Cefpimizole is used as an antibacterial agent for the treatment of various bacterial infections. Its narrow spectrum of activity allows for targeted treatment of specific bacterial strains, reducing the risk of collateral damage to beneficial bacteria and minimizing the potential for antibiotic resistance development.

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  • Pyridinium,1-[[(6R,7R)-2-carboxy-7-[ 5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt CAS 84880-03-5

    Cas No: 84880-03-5

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  • Hubei Jiutian Bio-medical Technology Co., Ltd
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  • Pyridinium,1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt

    Cas No: 84880-03-5

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  • Hangzhou J&H Chemical Co., Ltd.
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  • 84880-03-5 Structure

  • Basic information

    1. Product Name: Cefpimizole
    2. Synonyms: CEFPIMIZOLE;Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt;Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]-;U 63196;(6R,7R)-7-[[(2R)-2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino]-8-oxo-3-[[4-(2-sulfonatoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;1-[[(6R)-2-Carboxylato-7α-[[(R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)pyridinium;Cefpimizol;cefpimizole:(6r,7r)-7-(((2r)-2-((5-carboxy-1h-IMIDAZOLE-4-carbonyl)amino)-2-phenylacetyl)amino)-8-oxo-3-((4-(2-sulfonatoethyl)pyridin-1-ium-1-yl)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxyli
    3. CAS NO:84880-03-5
    4. Molecular Formula: C28H26N6O10S2
    5. Molecular Weight: 670.67
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 84880-03-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Cefpimizole(CAS DataBase Reference)
    10. NIST Chemistry Reference: Cefpimizole(84880-03-5)
    11. EPA Substance Registry System: Cefpimizole(84880-03-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84880-03-5(Hazardous Substances Data)

84880-03-5 Usage

Antimicrobial activity

A semisynthetic parenteral cephalosporin. It exhibits modest activity compared to other antipseudomonal cephalosporins. Like cefoperazone, it is susceptible to many enterobacterial β-lactamases. In volunteers receiving 0.1–1 g intramuscularly, mean peak plasma concentrations reached 15–20 and 35–40 mg/L, respectively. There was no accumulation when the dose was repeated every 8 h for 7 days. No metabolites have been detected. The plasma elimination half-life is 1.8– 2.1 h. The principal route of elimination is renal, 70–80% being recovered unchanged in the urine. Significant pain at the site of infection has been a prominent adverse event. It is no longer widely available.

Check Digit Verification of cas no

The CAS Registry Mumber 84880-03-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,8,8 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 84880-03:
(7*8)+(6*4)+(5*8)+(4*8)+(3*0)+(2*0)+(1*3)=155
155 % 10 = 5
So 84880-03-5 is a valid CAS Registry Number.
InChI:InChI=1/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1

84880-03-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Cefpimizole

1.2 Other means of identification

Product number -
Other names Cefpimizol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84880-03-5 SDS

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