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2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol, commonly known as quetiapine fumarate, is a pharmaceutical compound belonging to the class of atypical antipsychotics. It is utilized for the treatment of various mental health conditions by modulating the levels of specific neurotransmitters in the brain. Quetiapine fumarate is available in multiple formulations, such as immediate-release tablets, extended-release tablets, and oral suspension, and is generally well-tolerated with common side effects including drowsiness, dizziness, and weight gain.
Used in Pharmaceutical Industry:
2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol is used as a therapeutic agent for the treatment of mental health disorders such as schizophrenia, bipolar disorder, and major depressive disorder. It functions by affecting the levels of certain neurotransmitters in the brain, leading to an improvement in the symptoms associated with these conditions.
Used in Schizophrenia Treatment:
In the field of psychiatry, 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol is used as an atypical antipsychotic medication for managing the symptoms of schizophrenia. It helps in reducing positive symptoms like hallucinations and delusions, as well as negative symptoms such as social withdrawal and lack of motivation.
Used in Bipolar Disorder Management:
2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol is utilized as a mood stabilizer in the treatment of bipolar disorder, helping to control manic and depressive episodes. Its action on neurotransmitters aids in achieving a more balanced emotional state and reducing the severity and frequency of mood swings.
Used in Major Depressive Disorder Therapy:
In the context of major depressive disorder, 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol is employed as an adjunct therapy to enhance the effectiveness of antidepressant medications. It is particularly useful in cases where patients have not responded adequately to standard antidepressant treatments alone.
It is crucial to follow the guidance of a healthcare professional when using 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol, as abrupt cessation of the medication can lead to withdrawal symptoms.

848814-27-7

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848814-27-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 848814-27-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,8,1 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 848814-27:
(8*8)+(7*4)+(6*8)+(5*8)+(4*1)+(3*4)+(2*2)+(1*7)=207
207 % 10 = 7
So 848814-27-7 is a valid CAS Registry Number.

848814-27-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-amino-phenylsulfanyl)-phenyl-{4-(2-(2-hydroxyethoxy)ethyl)piperazin-1-yl}methanone

1.2 Other means of identification

Product number -
Other names 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:848814-27-7 SDS

848814-27-7Downstream Products

848814-27-7Relevant academic research and scientific papers

PREPARATION OF QUETIAPINE

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Page/Page column 8, (2008/06/13)

The present invention discloses a process for the preparation of quetiapine, which comprises the ring closure of a compound of the formula shown below, as well as novel intermediates in the process.

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