848821-19-2

Upstream product

• 51180-72-4 2-(2-propenyl)-4-pentenal 
• 52340-78-0 (R,R)-hydroxybenzoin 

Downstream Products

• 848821-20-5 (1S,3R,4R,6S,8R,10R)-6,10-bis(iodomethyl)-3,4-diphenyl-2,5,11-trioxabicyclo[6.3.0]undecane 
• 36170-05-5 rubrenolide 
• 848821-24-9 (3R,5R)-3-{2-(S)-[(1R,2R)-2-hydroxy-1,2-diphenylethoxy]-3-iodopropyl}-5-iodomethyldihydrofuran-2-one 
• 1030605-21-0 (3R,5R)-3-[(S)-2-((1R,2R)-2-Hydroxy-1,2-diphenyl-ethoxy)-3-iodo-propyl]-5-iodomethyl-tetrahydro-furan-2-ol 

Relevant academic research and scientific papers

Facile formation of tetrahydrofurans with multiple chiral centers using double iodoetherification of σ-symmetric diene acetals: short asymmetric total synthesis of rubrenolide and rubrynolide

A novel double intramolecular iodoetherification of σ-symmetric diene acetals from (R,R)-hydrobenzoin occurred in highly diastereoselective manners to give tetrahydrofuran moieties with multiple chiral centers in a one-pot operation. The chemoselective di

A double iodoetherification of σ-symmetric diene acetals for installing four stereogenic centers in a single operation: Short asymmetric total synthesis of rubrenolide

Tetrahydrofuran units with multiple chiral centers are formed in a highly diastereoselective manner through the one-pot double intramolecular haloetherification of σ-symmetric diene acetals (see scheme). The utility of the method was demonstrated by the s