848821-33-0Relevant academic research and scientific papers
A double iodoetherification of σ-symmetric diene acetals for installing four stereogenic centers in a single operation: Short asymmetric total synthesis of rubrenolide
Fujioka, Hiromichi,Ohba, Yusuke,Hirose, Hideki,Murai, Kenichi,Kita, Yasuyuki
, p. 734 - 737 (2005)
Tetrahydrofuran units with multiple chiral centers are formed in a highly diastereoselective manner through the one-pot double intramolecular haloetherification of σ-symmetric diene acetals (see scheme). The utility of the method was demonstrated by the s
Facile formation of tetrahydrofurans with multiple chiral centers using double iodoetherification of σ-symmetric diene acetals: short asymmetric total synthesis of rubrenolide and rubrynolide
Fujioka, Hiromichi,Ohba, Yusuke,Hirose, Hideki,Nakahara, Kenji,Murai, Kenichi,Kita, Yasuyuki
, p. 4233 - 4245 (2008/09/20)
A novel double intramolecular iodoetherification of σ-symmetric diene acetals from (R,R)-hydrobenzoin occurred in highly diastereoselective manners to give tetrahydrofuran moieties with multiple chiral centers in a one-pot operation. The chemoselective di
