848842-18-2

Basic information

• Product Name: 1,8-Naphthyridine, 2-chloro-3-(4-nitrophenyl)-
• CAS NO: 848842-18-2
• Molecular Formula: C14H8ClN3O2
• Molecular Weight: 285.689
• Mol File: 848842-18-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,8-Naphthyridine, 2-chloro-3-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridine, 2-chloro-3-(4-nitrophenyl)-(848842-18-2)
• EPA Substance Registry System: 1,8-Naphthyridine, 2-chloro-3-(4-nitrophenyl)-(848842-18-2)

Safety Data

• Hazardous Substances Data: 848842-18-2(Hazardous Substances Data)

Upstream product

• 60467-62-1 2-amino-3-(p-nitrophenyl)-1,8-naphthyridine 
• 555-21-5 4-Nitrophenylacetonitrile 
• 7521-41-7 2-Aminonicotinaldehyde 
• 848842-17-1 1,2-dihydro-3-(p-nitrophenyl)-1,8-naphthyridin-2-one 

Downstream Products

• 848842-19-3 2-hydrazino-3-(p-nitrophenyl)-1,8-naphthyridine 
• 848842-05-7 N-[1-(3,4-Dimethoxy-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-06-8 N-benzo[1,3]dioxol-5-ylmethylene-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-02-4 N-[1-(2,4-Dichloro-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-04-6 N-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-03-5 N-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848841-99-6 N-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-00-2 N-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848841-98-5 N-(4-methyl-benzylidene)-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 
• 848842-01-3 N-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-N'-[3-(4-nitro-phenyl)-[1,8]naphthyridin-2-yl]-hydrazine 

Relevant articles and documents

A Simple “Green” Synthesis of Novel Bis(3-aryl-1,8-naphthyridin-2-yl)sulfanes and 2-(Methylthio)-3-aryl-1,8-naphthyridines under Microwave Irradiation and Conventional Conditions

An eco-friendly and highly efficient synthesis of substituted bis(3-aryl-1,8-naphthyridin-2-yl)-sulfanes and 2-(methylthio)-3-aryl-1,8-naphthyridines under microwave and conventional conditions. The products are obtained with high yields and purity within short reaction time. The synthesized derivatives are screened for anti-microbial activity against bacteria and fungi. Molecular docking of the synthesized compounds with DNA Gyrase is studied.

Efficient synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using nitrous acid under microwave irradiation

A highly efficient, simple and rapid method for the synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines 8 by the oxidation of the corresponding aryl aldehyde 3-(p-nitrophenyl)-1,8-naphthyridin-2-ylhydrazones 7 using nitrous acid (NaNO2/CHsub