848844-32-6Relevant academic research and scientific papers
Inter- and intramolecular glycosylation of exo-glycals promoted by metallic Lewis acids
Hsu, Sheng-Jie,Lin, Hui-Chang,Lin, Chun-Hung
, p. 1428 - 1437 (2006)
exo-Glycosyl carbonates were employed for inter- and intramolecular glycosylation reactions. A number of metallic Lewis Acids and solvents were examined to enhance the reactivity. The optimum conditions were found to be the use of AlCl3 in 1-ni
Stereoselective glycosylation of exo-glycals by microwave-assisted Ferrier rearrangement
Lin, Hui-Chang,Chang, Chih-Chun,Chen, Jia-Yi,Lin, Chun-Hung
, p. 297 - 301 (2007/10/03)
exo-Glycosyl carbonates were shown to be efficient glycosyl donors in microwave-assisted glycosylation. In these reactions α-glycosyl additions occurred with excellent stereoselectivity and were complete in 4-8 min with 75-92% yield. Interestingly exo-glycals were found to have higher activity than endo-glycals and common glycosides, the reactions of which can be improved by the addition of Lewis acid to result in a higher yield and enhanced stereoselectivity.
