848908-96-3Relevant academic research and scientific papers
Bi(OTf)3-mediated intramolecular epoxide opening for bicyclic azepane synthesis
Zhu, Sha,Tran, Anh Tuan,Hirokami, Yuki,Gontard, Geoffrey,Khaled, Omar,Zhang, Yongmin,Kato, Atsushi,Blériot, Yves,Sollogoub, Matthieu
, p. 139 - 149 (2019/04/01)
While an epoxide on a sugar-derived aziridine studying was opened, an unexpected formation of bicyclic compounds was observed. The structure of these bicycles depended on the nature of the protecting group on the nitrogen atom of the aziridine. These comp
Nucleophilic opening of epoxyazepanes: Expanding the family of polyhydroxyazepane-based glycosidase inhibitors
Li, Hongqing,Schuetz, Catherine,Favre, Sylvain,Zhang, Yongmin,Vogel, Pierre,Sinay, Pierre,Bleriot, Yves
, p. 1653 - 1662 (2008/02/03)
A range of new tetra- and pentahydroxylated seven-membered iminoalditols has been efficiently synthesized from epoxyazepane precursors via nucleophilic opening with hydride or oxygenated species and subsequent hydrogenolysis. One tetrahydroxylated azepane
New 1-amino-1-deoxy- and 2-amino-2-deoxy-polyhydroxyazepanes: Synthesis and inhibition of glycosidases
Li, Hongqing,Bleriot, Yves,Mallet, Jean-Maurice,Rodriguez-Garcia, Eliazar,Vogel, Pierre,Zhang, Yongmin,Sinay, Pierre
, p. 313 - 319 (2007/10/03)
Eight new seven-membered ring iminoalditols, displaying an amino group and a hydroxymethyl group on the ring, have been synthesized from d-arabinose via epoxidation of a protected azacycloheptene and subsequent nucleophilic opening. Three of them show a p
