849-38-7

Upstream product

• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 500904-95-0 [2-(1H-indol-2-ylmethyl)phenyl]amine 
• 500904-99-4 1-bromo-1,3-bis(2-nitrophenyl)propan-2-one 
• 500904-96-1 methyl 2,3-bis(2-nitrophenyl)propanoate 
• 500904-97-2 3-(2-aminobenzyl)-2,3-dihydro-1H-indol-2-one 
• 243-38-9 6H-quinindoline 
• 114414-78-7 neocryptolepine 

Relevant academic research and scientific papers

Application of 7-endo-trig Pictet-Spengler cyclization to the formation of the benzazepine ring: Synthesis of benzazepinoindoles

The preparation of benzazepinoindoles, fused heterocycles with a benzazepine moiety, was accomplished through an intramolecular 7-endo-tring Pictet-Spengler cyclization. The precursors comprising C-3- or C-2-linked o-aminobenzyl-indoles required for the c

Synthesis of cryptolepine and cryptoteckieine from a common intermediate

Both cryptolepine 1 and cryptotackieine 3 have been synthesized from 1,3-bis(2-nitrophenyl)propan-2-one. The approach to 1 involved reduction of the NO2 groups, oxidative cyclization with PhI(OAc)2, and N-methylation, whereas 3 was obtained via bromination, Favorskii rearrangement, reduction (in situ cyclization), and N-methylation.