(Z)-3-Ureido-2-propenoic acid, also known as 2-iminoprop-2-enoic acid or N-(3-ureido-2-propenoyl)glycine, is a chemical compound with the molecular formula C5H6N2O3. It is a white, crystalline solid and belongs to the class of urea derivatives. (Z)-3-Ureido-2-propenoic acid is primarily recognized for its role as an inhibitor of the enzyme dihydroorotase, which plays a crucial part in the biosynthesis of pyrimidine nucleotides. Its ability to inhibit this enzyme makes (Z)-3-Ureido-2-propenoic acid a significant compound in pharmaceutical research and the development of new drugs for various diseases.
84902-98-7
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Basic information
- Product Name: (Z)-3-Ureido-2-propenoic acid
- Synonyms: (Z)-3-Ureido-2-propenoic acid
- CAS NO:84902-98-7
- Molecular Formula:
- Molecular Weight: 130.103
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (Z)-3-Ureido-2-propenoic acid(CAS DataBase Reference)
- NIST Chemistry Reference: (Z)-3-Ureido-2-propenoic acid(84902-98-7)
- EPA Substance Registry System: (Z)-3-Ureido-2-propenoic acid(84902-98-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 84902-98-7(Hazardous Substances Data)
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84902-98-7 Usage
Uses
Used in Pharmaceutical Research:(Z)-3-Ureido-2-propenoic acid is used as an enzyme inhibitor for dihydroorotase, which is involved in the biosynthesis of pyrimidine nucleotides. Its application is crucial in the development of new drugs for the treatment of various diseases, as inhibiting dihydroorotase can potentially disrupt the synthesis of essential cellular components, thereby affecting the growth and proliferation of disease-causing agents.
Used in Drug Development:
In the pharmaceutical industry, (Z)-3-Ureido-2-propenoic acid is used as a key compound in the design and synthesis of novel therapeutic agents. Its ability to inhibit dihydroorotase makes it a valuable starting point for creating drugs that target specific diseases by disrupting the biosynthesis of pyrimidine nucleotides, which are vital for the growth and replication of certain pathogens and cancer cells.
Used in Enzyme Inhibition Studies:
(Z)-3-Ureido-2-propenoic acid is also utilized in academic and research settings as a tool to study the function and inhibition of dihydroorotase. By understanding the interactions between (Z)-3-Ureido-2-propenoic acid and the enzyme, researchers can gain insights into the underlying mechanisms of pyrimidine nucleotide biosynthesis and identify potential targets for therapeutic intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 84902-98-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,9,0 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.Calculate Digit Verification of CAS Registry Number 84902-98:
(7*8)+(6*4)+(5*9)+(4*0)+(3*2)+(2*9)+(1*8)=157
157 % 10 = 7
So 84902-98-7 is a valid CAS Registry Number.
84902-98-7Upstream product
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(Z)-3-Ureido-2-propenoic acid
