849021-44-9 Usage
General Description
1-(5-Bromopyrimidin-2-yl)[1,4]diazepane is a chemical compound that consists of a 1,4-diazepane ring system with a bromopyrimidine substituent. It is a heterocyclic compound with potential biological activities that make it useful in the field of medicinal chemistry. The presence of the bromopyrimidine group in the molecule gives it unique properties that can be exploited for various applications, such as in drug development or as a research tool in chemical biology. Understanding the chemical structure and properties of 1-(5-Bromopyrimidin-2-yl)[1,4]diazepane is important for further exploration of its potential uses and applications in diverse scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 849021-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,0,2 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 849021-44:
(8*8)+(7*4)+(6*9)+(5*0)+(4*2)+(3*1)+(2*4)+(1*4)=169
169 % 10 = 9
So 849021-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H13BrN4/c10-8-6-12-9(13-7-8)14-4-1-2-11-3-5-14/h6-7,11H,1-5H2
849021-44-9Relevant articles and documents
Structure-Bioactivity Relationships of Lapatinib Derived Analogs against Schistosoma mansoni
Bachovchin, Kelly A.,Bag, Seema,Buskes, Melissa J.,Caffrey, Conor R.,Campbell, Robert F.,Clements, Monica,El-Sakkary, Nelly,Ferrins, Lori,Jalani, Hitesh B.,Klug, Dana M.,Leonard, Allison,Pollastri, Michael P.,Sciotti, Richard J.,Singh, Baljinder
supporting information, p. 258 - 265 (2020/03/30)
We recently reported a series of compounds for a solubility-driven optimization campaign of antitrypanosomal compounds. Extending a parasite-hopping approach to the series, a subset of compounds from this library has been cross-screened for activity against the metazoan flatworm parasite, Schistosoma mansoni. This study reports the identification and preliminary development of several potently bioactive compounds against adult schistosomes, one or more of which represent promising leads for further assessment and optimization.
