84905-75-9Relevant academic research and scientific papers
An efficient synthesis of 4,6-substituted pyrrolo[3,2-d]pyrimidines by silver-catalyzed cyclization of acetylene amine
Xie, Rui,Hu, Ying,Wan, Huixin,Hu, Yanwei,Chen, Shaohua,Zhang, Shilei,Zhang, Yinan
supporting information, p. 2418 - 2421 (2016/05/19)
A silver catalyzed cyclization of acetylene amine was developed to synthesize 4,6-substituted pyrrolo[3,2-d]pyrimidine, a bioactive isosteric scaffold of purine. Starting from simple commercially available acetylenes and pyrimidines, the method was found
