849062-37-9

Basic information

• Product Name: 3-Bromo-5-fluorophenylboronic acid
• Synonyms: 3-BROMO-5-FLUOROBENZENEBORONIC ACID 95;3-Bromo-5-fluorobenzeneboronic acid 95%;3-Bromo-5-fluorobenzeneboronic acid;3-Bromo-5-fluorophenylboronic acid
• CAS NO: 849062-37-9
• Molecular Formula: C₆H₅BBrFO₂
• Molecular Weight: 218.82
• Product Categories: blocks;BoronicAcids;Aryl;Boronic Acids;Boronic Acids and Derivatives
• Mol File: 849062-37-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: >300
• Boiling Point: 329.035 °C at 760 mmHg
• Flash Point: 152.795 °C
• Appearance: /
• Density: 1.75 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: Keep Cold
• PKA: 6.52±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 3-Bromo-5-fluorophenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-fluorophenylboronic acid(849062-37-9)
• EPA Substance Registry System: 3-Bromo-5-fluorophenylboronic acid(849062-37-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 849062-37-9(Hazardous Substances Data)

Usage

Uses

3-Bromo-5-fluorobenzeneboronic acid reactant for preparation of functionalized dihalophenylboronic acid via lithiation of dihalophenyl dioxazaborocines and reaction with electrophiles.

InChI:InChI=1/C6H5BBrFO2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,10-11H

Upstream product

• 1435-51-4 1,3-dibromo-5-fluorobenzene 

Downstream Products

• 1613643-93-8 C₅₂H₆₈F₂N₄O₈ 
• 7631-86-9 SiO₂ 
• 1160684-45-6 N-{[8-(3-bromo-5-fluorophenyl)-6-hydroxy-5-quinoxalinyl]carbonyl}glycine 
• 1160685-34-6 ethyl N-{[7-(3-bromo-5-fluorophenyl)-6-hydroxy-5-quinoxalinyl]carbonyl}glycinate 
• 1160685-35-7 ethyl N-{[7-(3'-bromo-5,5'-difluoro-3-biphenylyl)-6-hydroxy-5-quinoxalinyl]carbonyl}glycinate 

Relevant articles and documents

ALKYNYL ALCOHOLS AND METHODS OF USE

The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed.