849064-76-2Relevant academic research and scientific papers
Ruthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N-H Insertion: Synthesis of Benzofused Six-Membered Azaheterocycles
Padín, Damián,Saá, Carlos,Varela, Jesús A.
supporting information, (2020/03/30)
The Cp*RuCl-based catalyst enables expedient access to a variety of benzofused six-membered azaheterocycles from unprotected o-alkynylanilines and trimethylsilyldiazomethane through an unprecedent tandem carbene/alkyne metathesis/N-H insertion reaction. The transformation takes place under mild reaction conditions (room temperature, 15 min) and with excellent functional group tolerance. The synthetic utility of the final products and a mechanistic rationale are also discussed.
A new synthesis of 2,3-dihydrobenzo[1,4]dioxine and 3,4-dihydro-2H-benzo[1, 4]oxazine derivatives by tandem palladium-catalyzed oxidative aminocarbonylation - Cyclization of 2-prop-2-ynyloxyphenols and 2-prop-2-ynyloxyanilines
Gabriele, Bartolo,Salerno, Giuseppe,Veltri, Lucia,Mancuso, Raffaella,Li, Zhiyu,Crispini, Alessandra,Bellusci, Anna
, p. 7895 - 7898 (2007/10/03)
(Chemical Equation Presented) 2-[(Dialkylcarbamoyl)methylene]-2,3- dihydrobenzo[1,4]dioxine and 3-[(dialkylcarbamoyl)methylene]-3,4-dihydro-2H- benzo-[1,4]oxazine derivatives (3 and 5, respectively) were synthesized for the first time starting from readil
