84923-26-2 Usage
Chemical structure
pyrimidine-based compound
Functional groups
amino group, methoxy group, carboxamide group
Moieties
nortropane, methylbenzyl group
Potential biological activity
due to presence of pyrimidine ring
Potential pharmacological activity
due to presence of nortropane and methylbenzyl groups
Further research needed
to determine specific properties and potential uses
Check Digit Verification of cas no
The CAS Registry Mumber 84923-26-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,9,2 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 84923-26:
(7*8)+(6*4)+(5*9)+(4*2)+(3*3)+(2*2)+(1*6)=152
152 % 10 = 2
So 84923-26-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H27N5O2/c1-13-4-3-5-14(8-13)12-26-16-6-7-17(26)10-15(9-16)24-19(27)18-11-23-21(22)25-20(18)28-2/h3-5,8,11,15-17H,6-7,9-10,12H2,1-2H3,(H,24,27)(H2,22,23,25)
84923-26-2Relevant articles and documents
Studies on the neuroleptic benzamides. III - Synthesis and antidopaminergic properties of new 3-nortropane derivatives
Dostert,Imbert,Langlois,et al.
, p. 105 - 110 (2007/10/02)
Various benzamides prepared from 4-alkoxy pyrimidine 5-carboxylic acids and 3-amino nortropane derivatives have been tested for their potential antipsychotic activity. Two compounds exhibited pharamacological activity equivalent to that of haloperidol but had lower toxicity and lower potency to induced catalepsy. Antidopaminergic activity is observed mainly in compounds in which the nortropane ring is substituted in the equatorial position, having a benzyl substituent on the basic nitrogen. The influence of electron attractor or donor substituents carried by the benzyl ring has been evaluated. Some aspects of structure-activity relationships are discussed.