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849235-53-6

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849235-53-6 Usage

2-Amino-4-(thien-2-yl)nitrobenzene

Chemical structure: nitrobenzene core with thien-2-yl and amino groups attached
Potential applications: pharmaceutical or chemical industries
Suitable for: organic synthesis, building blocks for complex molecules
Biological activity: potential drug candidates or medicinal purposes

2-(3-Amino-4-nitrophenyl)thiophene

Chemical structure: thiophene core with phenyl and amino groups attached
Potential applications: pharmaceutical or chemical industries
Suitable for: organic synthesis, building blocks for complex molecules
Biological activity: potential drug candidates or medicinal purposes

Check Digit Verification of cas no

The CAS Registry Mumber 849235-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,2,3 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 849235-53:
(8*8)+(7*4)+(6*9)+(5*2)+(4*3)+(3*5)+(2*5)+(1*3)=196
196 % 10 = 6
So 849235-53-6 is a valid CAS Registry Number.

849235-53-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-nitro-5-thiophen-2-ylaniline

1.2 Other means of identification

Product number -
Other names 2-nitro-5-thiophen-2-yl-phenylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:849235-53-6 SDS

849235-53-6Relevant articles and documents

Synthesis and antimicrobial activity of novel substituted 4-[3-(1H-benzimidazol-2-yl)-4-hydroxybenzyl]-2-(1H-benzimidazol-2-yl)phenol derivatives

Anil,Shankar,Bharath,Jalapathi

, p. 2648 - 2653 (2017/12/26)

A series of novel substituted bis-benzimidazole derivatives were synthesized by reaction of 5,5′-methylenebis(2-hydroxybenzaldehyde) with various substituted o-phenylenediamines in glacial acetic acid. The structure of the newly synthesized compounds was elucidated by 1H and 13C NMR, FT-IR, and MS spectra, and their antimicrobial activity against gram positive and gram negative bacteria and antifungal activity were evaluated. The thienyl-substituted derivative showed significant activity against Bacillus licheniformis. Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumonia (bacteria), and Fusarium solani (fungi). The activities of the fluoro-substituted substituted derivative against some bacterial strains and of the thienyl-substituted derivative against fungi were found to be similar to those of standard drugs.

Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity

Moradei, Oscar M.,Mallais, Tammy C.,Frechette, Sylvie,Paquin, Isabelle,Tessier, Pierre E.,Leit, Silvana M.,Fournel, Marielle,Bonfils, Claire,Trachy-Bourget, Marie-Claude,Liu, Jianhong,Yan, Theresa P.,Lu, Ai-Hua,Rahil, Jubrail,Wang, James,Lefebvre, Sylvain,Li, Zuomei,Vaisburg, Arkadii F.,Besterman, Jeffrey M.

, p. 5543 - 5546 (2008/03/27)

Significant effort is being made to understand the role of HDAC isotypes in human cancer and to develop antitumor agents with better therapeutic windows. A part of this endeavor was the exploration of the 14 ? internal cavity adjacent to the enzyme catalytic site, which led to the design and synthesis of compound 4 with the unusual bis-(aryl)-type pharmacophore. SAR studies around this lead resulted in optimization to potent, selective, nonhydroxamic acid HDAC inhibitors.

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