849241-91-4

Basic information

• Product Name: 6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine
• Synonyms: 6-Chloro-9-(3-C-Methyl-β-D-ribofuranosyl)-9H-purine;6-chloro-9H-(3-C-Methyl-β-D-ribofuranosyl)purine;6-Chloro-9-(3-C-Methyl-b-D-ribofuranosyl)-9H-purine;6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine
• CAS NO: 849241-91-4
• Molecular Formula: C11H13ClN4O4
• Molecular Weight: 300.69832
• Mol File: 849241-91-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 590.081 °C at 760 mmHg
• Flash Point: 310.67 °C
• Appearance: /
• Density: 1.86
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine(849241-91-4)
• EPA Substance Registry System: 6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine(849241-91-4)

Safety Data

• Hazardous Substances Data: 849241-91-4(Hazardous Substances Data)

Usage

Description

6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine, also known as cladribine, is a synthetic purine nucleoside analog with antineoplastic and immunosuppressive properties. It is a promising pharmaceutical agent for the treatment of various conditions, including cancer and autoimmune diseases, due to its ability to interfere with DNA synthesis and repair in cancer cells and suppress the activity of certain immune cells.

Uses

Used in Oncology:
6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine is used as an antineoplastic agent for the treatment of hairy cell leukemia, a rare type of cancer affecting the blood and bone marrow. It works by disrupting DNA synthesis and repair in cancer cells, ultimately leading to their death.
Used in Autoimmune Disease Treatment:
6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine is used as an immunosuppressive agent in the treatment of autoimmune diseases such as multiple sclerosis. Its ability to suppress the activity of certain immune cells helps manage the symptoms and progression of these conditions.
Used in Pharmaceutical Industry:
6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine is used as a key ingredient in the development of pharmaceutical drugs targeting cancer and autoimmune diseases. Its unique properties make it a valuable component in the formulation of effective treatment options.
Administration:
6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine is administered as an intravenous infusion or subcutaneous injection, allowing for targeted delivery to the affected areas and ensuring optimal therapeutic effects.
Safety Considerations:
While generally well-tolerated, 6-Chloro-9-(3-C-methyl-beta-D-ribofuranosyl)-9H-purine may increase the risk of infections and should be used with caution in individuals with pre-existing immunosuppression. Patients should be closely monitored for any side effects and appropriate adjustments made to the treatment plan as needed.